Nucleophilic Fluorination of aromatic radionuclide compounds for Molecular Imagine technique

Dr. Sachin U Kalme

doi:10.59367/jy79g736

Authors

Dr. Sachin U Kalme Department of Chemistry, S.S.J.E.S., Arts, Commerce & Science College, Gangakhed, Dist. Parbhani- 431514, MS, India

DOI:

https://doi.org/10.59367/jy79g736

Keywords:

nucleophilic fluorination, TBAF, tert-alcohol, and fluorinated compounds.

Abstract

Our aim is the synthesis of ¹⁸F- radiolabeled drug molecules for the Positron emission tomography (PET), it is a functional imaging technique with important clinical applications in cardiology, oncology, and neurology. Our major work on the selective fluorination of aromatic compounds because of fluoroaromatic are important intermediates in the pharmaceutical especially in molecular imagine technique.

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